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Post Doctoral Scientist - Biomedical Imaging and Vascular Biology

Requisition ID: 2024-49107
Overview: Dr. Mitchel Stacy Lab | | A postdoctoral research position is immediately available within the Center for Regenerative Medicine at Nationwide Children’s Hospital working in the lab of Dr. Mitchel Stacy. | | Research in the lab is focused on the development and validation of quantitative imaging techniques that allow for characterization of cardiovascular diseases and vascular remodeling. Of particular interest is PET imaging of skeletal muscle perfusion and PET-based molecular imaging of vascular biology. | | The lab utilizes multiple imaging modalities, which include clinical and microPET/CT, CT angiography, and ultrasound. The lab is equipped with a variety of image processing workstations, which include dedicated software for PET/CT image analysis, ANSYS for computational modeling research, dedicated tools for ultrasound image analysis, and a dedicated angiography workstation. Experimental work and training will be focused on pre-clinical models of vascular disease (small and large animal) and clinical cardiovascular imaging. Clinical imaging projects will be conducted in collaboration with The Ohio State University College of Medicine and additional pediatric hospitals across the United States. | | Candidates should be highly motivated with an interest in biomedical imaging, vascular biology, and/or skeletal muscle biology. Also required are excellent written and verbal communication skills, as the position will involve participation in manuscript and grant writing. | | To apply, interested individuals should send a letter of interest and recent copy of CV to Dr. Stacy at mitchel.stacy@nationwidechildrens.org | For more information related to the lab’s research, please refer to a list of recent publications... | https://www.ncbi.nlm.nih.gov/myncbi/14IZpslMVRrAt/bibliography/public/

Post Doctoral Scientist - Cardiovascular/Heart/Stem Cells

Requisition ID: 2024-48901
Overview: Dr. Deqiang Li Lab | | A fulltime position postdoctoral fellow position is immediately available in Dr. Deqiang Li’s Laboratory, in the Center for Cardiovascular Research at the Nationwide Children’s Hospital (NCH) Research Institute, Ohio State University. This position is supported by a NIH R01 grant. | | Read about Dr. Li's Research Program here: | Deqiang Li (nationwidechildrens.org) | | Research in my laboratory is focused on understanding the mechanisms of cardiovascular development, disease, and regeneration. In particular, we are interested in identifying the novel signaling pathways that regulate myocardial development or govern cardiomyocyte differentiation and maturation by using in vitro and in vivo approaches. | | Cell and mouse model systems, including induced pluripotent stem cells (iPSCs) and conditional gene knockouts will be used in these research projects. Many state-of-the-art techniques are employed, such as CRISPR/Cas9 Genome Editing, AAV, single cell RNA-Seq and ChIP Seq, confocal microscopy, multicolor flow and sorting, surgical models, ultrasonic and telemetric measurements of cardiovascular function in mice.

Faculty Position - Cardiovascular Scientist

Requisition ID: 2024-48041
Overview: The Center for Cardiovascular Research in the Abigail Wexner Research Institute at Nationwide Children's Hospital is expanding its faculty. The primary mission of this Center is to transform the care of children, adolescents, and young adults with congenital heart disease and acquired pediatric heart diseases through research and clinical translation. More information is available at: | | Center for Cardiovascular Research (nationwidechildrens.org) | | About the Faculty Position: | - Seeking Assistant, Associate, or Full Professor (Tenure Track at The Ohio State University College of Medicine) | - Candidates should have a research laboratory focused on pediatric cardiovascular disease and/or relevant basic science area | - Scientific areas of particular interest include blood vessel biology, gene therapy for cardiovascular disease, cardiac metabolism, and bioinformatics/data science | - Will establish an independent research program | - Will help revolutionize the prevention, diagnosis and treatment of cardiovascular disease in children | Qualifications Required: | - MD, MD/PhD, or PhD | - Strong track record of publishing in high quality journals | - Current K-award, R01 or equivalent independent grant funding is highly desired | About the Center for Cardiovascular Research: | - The Center for Cardiovascular Research integrates basic, translational, and clinical research programs to advance discovery of innovative diagnostic and treatment tools that will address major challenges in the field of cardiovascular science | - New faculty members will have strong ties to The Heart Center which houses the clinical cardiac program | - Principal Investigators are also Faculty members at The Ohio State University College of Medicine | | Send correspondence, including curriculum vitae, a brief statement of research interests, and contact information for three references to Patrick.Kennedy@nationwidechildrens.org in Faculty Recruitment. | | | ABOUT THE RESEARCH INSTITUTE: | - Top ten among free-standing children’s hospitals for NIH funding | - Designed for collaboration, creativity, and team science | - Comprehensive resources including regulatory support, tech transfer, genomics, and GMP facility | ABOUT NATIONWIDE CHILDREN’S HOSPITAL: | - Among largest pediatric hospitals in the US: 1M+ patient visits annually | - Nationally recognized for diversity and inclusion | - US News & World Report Honor Roll hospital | ABOUT COLUMBUS, OHIO: | - State capital with 2M+ population | - Forbes #1 rising city for startups | - Outstanding quality of life and cost of living | Through our diversity, we achieve the highest standards of inclusiveness and create a culture that respects individual differences. It is the cornerstone of our strategic plan and how we attract the best people to ensure the best programs. To build a diverse workforce, Nationwide Children’s encourages applications from individuals with disabilities, minorities, veterans, and women. EEO/AA employer.

Post Doctoral Scientist - Cardiovascular/Stem Cells/Genomics

Requisition ID: 2023-47763
Overview: A postdoctoral scientist position is immediately available in Dr. Mingtao Zhao’s laboratory in the Center for Cardiovascular Research at the Nationwide Children’s Hospital and The Ohio State University in Columbus, Ohio. The Zhao lab is using patient-derived induced pluripotent stem cells (iPSCs), CRISPR/Cas9 genome editing, organoids, and single-cell genomics to study the molecular and genetic mechanisms of cardiovascular development and congenital heart disease (Circ Res 2023, PMID: 36583388; Stem Cell Res 2023, PMID: 36599283; Stem Cells 2020, PMID: 32232889; PNAS 2017, PMID: 29203658; Circ Res 2017, PMID: 29030344). | | The goal of the Zhao lab is to elucidate the cause-consequence relationship of a given genetic variant in the contribution of cardiovascular disease using patient-specific iPSCs that retain all genetic information of the affected patients. The Zhao lab is currently funded by the NIH/NHLBI, Additional Ventures, AHA, and Abigail Wexner Research Institute at Nationwide Children’s Hospital. | | Qualifications Required: | | This is a great opportunity for young investigators who aim to establish an independent academic career in the next few years. Successful candidates should have a PhD/MD or equivalent degree (< 3 years after graduation) and should have expertise in cardiac physiology, cardiovascular development, genomics, or organoid biology. Candidates who have additional expertise in bioinformatics or CRISPR/Cas9 genome editing or tissue engineering would be preferred. Individuals who are underrepresented in the biomedical research are encouraged to apply. Candidates will have an opportunity to be funded by an NIH T32 training award. Competitive salary and relocation bonus will be offered for well-qualified candidates. | | The Center for Cardiovascular Research currently has an NIH-funded T32 postdoctoral program to provide interdisciplinary, translational, and state-of-the-art research training in congenital and acquired heart disease, partnered with The Ohio State University College of Medicine. The Abigail Wexner Research Institute is one of the largest pediatric research centers and consistently ranked among the top 10 for NIH funding among free-standing children’s hospitals in the United States. In addition, Nationwide Children’s Hospital has been consistently ranked on the US News & World Report’s “America’s Best Children’s Hospitals Honor Roll”. | | Potential candidates should send their CV (with publication list) to | | Mingtao Zhao, PhD | Principal Investigator | Center for Cardiovascular Research | Nationwide Children’s Hospital | Assistant Professor | Departments of Pediatrics | The Ohio State University | TEL: 614-355-6748 | Email: Mingtao.Zhao@nationwidechildrens.org

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