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Associate Director - Research- ARC

Requisition ID: 2024-50059
Overview: This position is multifaceted involving administrative, regulatory, and veterinary activities. This position develops and manages the clinical and technical veterinary program, including the aquatics program. In addition, provides clinical oversight/support for research animal care and use, medicine, disease, diagnosis, and experimental techniques for researchers at the Abigail Wexner Research Institute. Ensures research and clinical activities adhere to the United States Department of Agriculture (USDA), Public Health Service (PHS), and AAALAC rules and regulations. In the event the Director/Attending Veterinarian is absent, the Associate Director will assume all responsibilities to lead the department.

Research Associate - Center for Gene Therapy- Wein

Requisition ID: 2024-50052
Overview: The Wein Lab is focusing on Neuromuscular Disorders such as Duchenne Muscular dystrophy, which is a devastating disease leading to death of patients at age 20-30 years. Our lab developed an expertise in translational research, an emerging field which can be summarized as understanding the cause of a disease and learning from it in order to develop innovative therapeutic strategies. We are fully committed to continuing to integrate basic science and gene therapy skills in order to advance understanding and treatment of the muscular dystrophies. Our lab long term project focus on RNA and DNA editing and gene transfer as therapies for neuromuscular disorders, but it will also include more fundamental research on muscle function. In particular, our lab uses most recent technologies such as virus-mediated exon-skipping and the CRISPR/Cas9 genome editing tool. We are looking for a highly motivated research associate person who is energetic and intelligent to join our dynamic team. In particular, we are looking for someone with experience in molecular biology (qPCR, IF, WB), as well as mouse injection and dissection experiences for neuromuscular disorders. Experience in dissecting and mounting muscle tissue is preferred. No background in gene therapy is required, however the person should have a high interested in human genetics and diseases and should be eager to learn and work on the bench in an independent manner. Finally, our team relies on good teamwork and therefore, the candidate should be a good communicator and team player. The job description includes, but is not restricted to performing research experiments, maintaining records of experiments, preparing laboratory reports, analyzing data and preparing publications and grants applications.

IGM Chief Research Associate- Neurosurgery

Requisition ID: 2024-50043
Overview: Manages daily operations in the lab, supervises and trains staff on procedures, and ensures that the standard operation procedures and quality control program is compliant. Provides on-call coverage for section on rotating basis on holidays and weekends.

IGM Medical Laboratory Assistant- IGM

Requisition ID: 2024-49985
Overview: IGM Medical Lab Assistant | | We are seeking an IGM Medical Laboratory Assistant to join our team. The Medical Lab Assistant is responsible for clerical and patient care support tasks which enable technologists to complete testing of patient specimens in a timely manner.

Research Intern- RI Vaccines & Immunity Peeples

Requisition ID: 2024-49969
Overview: Provides assistance in research experiments under direction of Research Assistant; obtains supplies and equipment needed for research projects; maintains laboratory records.

Clinical Research Coordinator I - RI Biobehavioral Nelson

Requisition ID: 2024-49960
Overview: A full-time Clinical Research Coordinator is being recruited for a collaborative research team investigating the relationship between brain development and mental wellbeing in youth. The successful candidate will contribute multiple ongoing studies examining the neuroanatomical and functional substrates that contribute to cognitive, social and emotional functioning in both medical populations and healthy youth. Duties will involve direct work with research participants (recruitment, in-person data collection), including helping to execute study visits involving magnetic resonance imaging (MRI), neurocognitive assessment, data management, statistical analyses, and dissemination of research results. Data management will include scoring standardized assessments, medical record reviews, data entry and verification, and training in the processing of neuroimaging data. This position will involve close collaboration with the principal investigator, as well as other research staff and investigators at NCH and medical staff at NCH/The Ohio State University. Opportunities exist for mentorship and professional development for applicants who are interested in gaining experience that will prepare them to apply for advanced graduate programs, particularly in clinical psychology, neuropsychology, or neuroscience. In addition to mentorship provided by the lab principal investigator, lab members have the option to participate in the Center for Biobehavioral Health Post-Baccalaureate Program, which is dedicated to aiding staff in identifying and understanding career paths and managing the application process for various fields’ graduate programs. Applicants are encouraged to submit resumes with sufficient detail to demonstrate their academic record (i.e., college GPA) and relevant research or work experience. Cover letters are encouraged.

Research Intern - RI CIRP -Yang

Requisition ID: 2024-49958
Overview: The Center for Injury Research and Policy, located in The Research Institute of Nationwide Children's Hospital in Columbus, Ohio, is seeking a summer internship position in injury research. The person in this position will under the supervision of the principal investigator, Dr. Ginger Yang and will assist in sports injury research conducted by Dr. Yang?s research team. | Dr. Yang?s research is highly collaborative and includes collaborations with the researchers both inside and outside of The Ohio State University. | The Center for Injury Research and Policy is one of 11 CDC-funded Injury Control Research Centers and focuses on the prevention of injury among children and adolescents. Its faculty members are active in injury research and prevention at local to global levels. Center faculty members teach and mentor students at The Ohio State University and from across the nation. Its global injury research program includes ongoing projects with its affiliate faculty in low- and middle-income countries and a visiting scholars program. Through multiple partnerships, the Center has established collaborative networks of injury professionals regionally, nationally and globally. A translational research team helps faculty members disseminate their research findings.

Research Associate Sr.- Center for Gene Therapy - Harper

Requisition ID: 2024-49957
Overview: Senior Research Associate in Gene Therapy | | Employer: Center for Gene Therapy, The Abigail Wexner Research Institute at Nationwide Children’s Hospital | | Location: Columbus, Ohio, USA | | Salary: Competitive salary based on the candidate’s experience, benefits include family health insurance, matched retirement account | | Discipline: Life Sciences, Gene Therapy, Cellular and Molecular Biology, RNAi, CRISPR, Neurological diseases, Peripheral Neuropathy, neuromuscular diseases, Adeno-Associated Viral (AAV) vectors, Immunology, | | Start Date: As soon as possible | | Position Type: Full-time | | Organization Type: Non-profit | | The Harper Lab at the Center for Gene Therapy at Nationwide Children’s Hospital (NCH) is focused on developing gene therapies for muscular dystrophies and neuropathies. We are seeking a highly motivated, experienced, and independent Senior Research Associate to join our energetic, diverse and innovative team. We do molecular, cellular, and in vivo work. The ideal candidate will have experience in molecular biology and biochemistry (e.g. molecular cloning, western bloting, qPCR, various in vitro assays, and cell culture), as well as show talent or promise in scientific writing. Pre-clinical work in animal models may also be needed. This person will develop and validate new protocols for in vitro and in vivo experiments and will be responsible for training and directing junior lab members. A strong candidate will also have outstanding organization skills. | | The Harper Lab operates as a team and we promote and esprits de corps and work-life balance. Our philosophy centers on the notion that productivity is more important than time spent in the lab, and although we seek an individual capable of working on-site daily, we are open to flexible working hours. | | This position includes excellent retirement and health insurance benefits.

Clinical Research Coordinator I - RI Biobehav Skeens

Requisition ID: 2024-49956
Overview: A full-time Research Coordinator is being recruited for a collaborative research team that is focused on examining family adjustment to children’s life-threatening conditions, such as cancer. The successful candidate will contribute to ongoing work with children and adolescents with cancer. Duties will involve direct work with research participants (recruitment, in-person data collection) in the hospital, schools, and family homes, as well as study coordination. Specific tasks may include: helping with IRB protocols, helping to execute study visits, interviews, data management and analyses, and dissemination of research results. This position will involve close collaboration with the investigators as well as other research staff at NCH and medical staff at NCH/Ohio State University. Several opportunities exist for mentorship and professional development for applicants who may be interested in gaining experience that will prepare them to apply for advanced graduate programs in medicine or psychology. A two-year commitment is required. Some evening and weekend hours may be required to accommodate data collection efforts. Applicants are encouraged to submit resumes with sufficient detail to demonstrate their academic record (i.e., college GPA) and relevant research or work experience. Cover letters are encouraged. The Clinical Research Coordinator’s primary responsibility is managing elements of a clinical study in order to meet all protocol obligations while following ICH/GCP guidelines; and departmental/institutional standard operating procedures. These elements include but are not limited to; start-up activities, launch activities, day to day management of a study and study closure activities.

ODS Data Sciences Strategy & Applications Lead

Requisition ID: 2024-49955
Overview: The Lead, Data Sciences Strategy and Applications, occupies a vital leadership position within the Office of Data Sciences at the Abigail Wexner Research Institute. This role demands a visionary leader with extensive experience in software development for data sciences applications, focusing on bioinformatics, computational genomics, data visualization, and leveraging big data in biomedical health sciences research. The successful candidate will lead a team in developing sophisticated data solutions that incorporate machine learning, advanced language models, statistical analysis, and data visualization techniques to address the complex challenges of biomedical data science.

Post Doctoral Scientist Yr 1-3 - IGM Bedrosian

Requisition ID: 2024-49950
Overview: The Bedrosian lab in the Institute for Genomic Medicine is seeking a post-doctoral scientist to join our team. Our translational research group focuses on studying the genetics of epilepsy and other neurodevelopmental diseases using patient-derived tissue as well as murine models. We use cutting-edge techniques including single cell RNA-sequencing, spatial transcriptomics/proteomics, and other genomic techniques. The successful candidate will be engaged in projects exploring the molecular etiology of epilepsies through bioinformatic analysis of single-cell sequencing data and other genomic data. Prior experience with R and Seurat is preferred. The Institute for Genomic Medicine provides a stellar training environment with exposure to world-class expertise in genomics. We are a collaborative group with opportunities to build new skillsets and interact across the institute. Post-doctoral scientist will report to PI.

Research Purchasing Coordinator

Requisition ID: 2024-49935
Overview: The Purchasing Coordinator works under the supervision of the Purchasing Manager and is responsible for maintaining the efficient flow of purchase order requisitions and assisting with the placing of routine orders. This position works closely with internal customers to resolve order issues and supply interruptions. This position additionally works with Supply Chain staff to address supply concerns and update the SCIS system.

Post Doctoral Scientist - Gene Therapy/Neuroscience

Requisition ID: 2024-49922
Overview: EMPLOYER: Gene Therapy LaboratoryAbigail Wexner Research Institute, Nationwide Children’s Hospital (NCH). | | LOCATION: Columbus, Ohio, USA | | POSITION TYPE: Full-time | | PREFERRED START DATE: April 2024 | | DISCIPLINE: Gene Therapy | | ORGANIZATION TYPE: Non-profit | | RESEARCH DESCRIPTION: Our group is focused on developing novel gene therapy treatments for neuromuscular disorders and lysosomal storage disorders. We have recently developed and tested a novel gene therapy in patients with Duchenne Muscular Dystrophy and are currently developing treatments for Limb Girdle Muscular Dystrophy Type R9, GNE myopathy, and Lysosomal Acid Lipase Deficiency. This research involves basic and proof of concept studies in animal models for these diseases, as well as safety studies, with the goal of developing IND approvals for the testing of therapies in clinical trials. We collaborate with a team of other laboratories in Center for Gene Therapy and at Ohio State University to accomplish these goals. | | The successful candidate will have an excellent foundation in molecular and cellular biology and also in molecular and cellular pathology. We are particularly interested in candidates who also have experience analyzing animal models of disease and who understand the concepts relevant to design of disease therapies for muscle, liver, and/or brain disorders. As our lab focuses on diseases and therapies involving glycosylation, experience in glycobiology would be a major plus. Expertise in skeletal muscle or cardiac physiology, or AAV biology, would also be a major plus. To apply, please submit curriculum vitae, a cover letter indicating areas of expertise and a detailed statement of research interests and scientific accomplishments, and a list of 3 references. | | The selected candidate will be professional, self-motivated, and dedicated, with strong communication and interpersonal skills that will fit with our highly collaborative team. You will have many opportunities to learn new skill sets, present your work, develop professionally, and contribute to identifying new therapies for children with genetic disorders. | | **This position offers candidates to be involved in basic research and translation to the clinic** | | QUALIFICATIONS: | - Applicants must have an MD, Ph.D., or MD/PhD in a field of Biomedical or Life Sciences. | - Previous experience in a wet lab including work with cell cultures and animal models is required. | | COMPETENCIES, KNOWLEDGE, SKILLS, AND ABILITIES: | - Candidates should be capable of designing and carrying out high-level, complex research experiments independently. | - Expertise in lab techniques including, but not limited to, immunofluorescence, western blotting, ELISA, qPCR, qRT-PCR, flow cytometry, protein biochemistry, glycobiology, etc. | - Applicants with a good track record of publication are desirable, along with effective communication skills and scientific writing skills. | - Ability to train and mentor laboratory staff and graduate students. | - Writing and publishing scientific material, including manuscripts. | - Presenting research at regional, national, and international conferences. | - Contributing to grant submissions for external funding. | | We can offer potential candidates: | - Up to 5 years of salary support, to be renewed annually based on productivity | - Strong mentorship to support career development toward academia or industry jobs | - State-of-the-art laboratories and core facilities | - Possible affiliation with The Ohio State University College of Medicine | - Collaborative initiatives with clinical faculty

Research Associate- Research Institute Gene Therapy Martin

Requisition ID: 2024-49921
Overview: Conducts independent research related to muscle disease in conjunction with a Principal Investigator; assists in the preparation of scientific publications and research grant proposals; prepares budget proposals for conducting research studies.

Lab Support Associate - RI Biopath Moyer

Requisition ID: 2024-49914
Overview: The Biopathology Center (BPC) within The Research Institute at Nationwide Children’s Hospital is a primarily grant-funded biorepository with the objective of acquisition and long-term storage of a large number of cancerous, normal and diseased biospecimens and related data. These biospecimens are used to support and facilitate cutting edge research and advancing clinical patient care. In accordance with provisions of approved protocols, the BPC currently serves as biorepositories for the Children’s Oncology Group (COG), NRG Oncology, SWOG (formerly the Southwestern Oncology Group), the Pediatric Division of the Collaborative Human Tissue Network (pCHTN), internal investigators, and other sponsor groups. This is a fast-paced, team-oriented laboratory that requires the ability to work well under pressure and maintain constant attention to detail. The position requires frequent communication via phone and email with submitting institutions as well as internal coordinating laboratories. This role does not perform hypothesis-based research or analysis on the biospecimens – we serve a supporting role to facilitate research. The Lab Support Associate is responsible for providing clerical and general support to the Biospecimen Processing and Receiving Laboratory. Duties include, but are not limited to, transportation of specimens, providing effective communication with regards to specimens and collection information, and providing an appropriate link to other lab sections when needed. Should project a professional image through direct and indirect communication to both internal and external Nationwide Children’s Hospital customers.

Research Associate - Research Childhood Cancer- Cassady

Requisition ID: 2024-49882
Overview: Research Assoc., Research Institute at Nationwide Children’s Hospital, Columbus, OH. Coordinate activities of tech & prof employees engaged in lab research. Ensure research experiments & lab analyses are performed in accordance w/guidelines. Conduct independent research studies & lab analysis. Set up research experiments. Collect & analyze data in accordance w/statistical procedures & prepare reports of results of studies. Collaborate & interact w/researchers onsite & at other research institutions. Prepare position papers about research studies, incl info about difficulties encountered in setting up & conducting research studies. Assist in prep of scientific publications & grant proposals w/regard to a specific area of research. Attend scientific conferences & give scientific presentations. Prepare budget proposals for supplies & equipment. Min. req incl: Bachelor’s in Biology, Molecular Biology, Microbiology or related, plus 2 yrs exp, incl ability to independently design & conduct experiments (in-vitro cell culture & molecular biology work, in-vivo animal work, such as implant tumors, inject tumors, resect tumors, perform intraperitoneal injections, collect & process animal organs, etc.); ability to collect & analyze data; ability to conduct immunological experiments (ELISA, flow cytometry); & knowledgeable in basic virology & in creating attenuated virus. Send resume to marsha.lutz@nationwidechildrens.org.

Research Assistant - ENT

Requisition ID: 2024-49878
Overview: The Research Assistant performs research experiments and clinical studies in accordance with provisions of the approved protocol; maintains records of experiments and prepares laboratory reports; assists in analyzing data and preparing publications.

Research Intern - RI Regenerative Med Stacy

Requisition ID: 2024-49872
Overview: Provides assistance in research experiments under direction of Research Assistant; obtains supplies and equipment needed for research projects; maintains laboratory records.

Research Intern - RI Injury Leonard

Requisition ID: 2024-49865
Overview: The Center for Injury Research and Policy (CIRP), located in The Abigail Wexner Research Institute at Nationwide Children's Hospital (NCH) in Columbus, Ohio, is seeking a part time student to join the Leonard Lab. The Research Intern will work on child and adolescent injury research projects that focus on injury, emergency medicine and emergency medical services. The person in this position will be responsible for assisting on several research projects with our collaborators within NCH, Columbus Division of Fire, the Ohio Department of Public Safety and the Pediatric Emergency Care Applied Research Network, under the supervision of the principal investigator (PI), Dr. Julie Leonard.

Research Intern - RI IGM Warren

Requisition ID: 2024-49864
Overview: Research Intern- IGM | | Provides assistance in research experiments under direction of Research Assistant; obtains supplies and equipment needed for research projects; maintains laboratory records.

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