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IGM - Bioinformatics Software Developer

Requisition ID: 2024-50124
Overview: IGM Bioinformatics Software Developer I | | | Overview | | Full-time: Main Campus/Remote/Hybrid, Mon-Fri | | We are looking for a candidate who can work closely with faculty and staff to design and build efficient instrument-to-interpretation pipelines for next-generation sequencing (NGS) workflows, optimizing outcomes for our genomic medicine initiatives. It is expected that the individual in this position will possess strong software development abilities, enjoys solving complex problems and has a desire to make an impact in medical research and patient care. The candidate will also be encouraged to participate in bioinformatics related discussions, group meetings and presentations for the Institute for Genomic Medicine (IGM).

IGM Bioinformatics Analyst I

Requisition ID: 2024-50115
Overview: IGM Bioinformatics Analyst I | | We are looking for a candidate that will assist in all aspects of next-generation sequencing analysis including data generation, analysis, interpretation, and publication. This entry-level position involves maintaining, running, and troubleshooting genomic pipelines for next-generation sequencing assays in clinical, translational and research settings. The ideal candidate will possess strong data processing and data quality control abilities, enjoy solving complex problems and have a desire to make an impact in medical care through advancing our understanding of the role of the human genome in disease. The candidate will also be encouraged to participate in bioinformatics related discussions, group meetings and presentations for the Institute for Genomic Medicine (IGM). Previous experience in bioinformatics or a computational biological background is preferred but not required for this position.

Research Faculty Transition & Integration Coordinator

Requisition ID: 2024-50111
Overview: The Research Faculty Transition and Integration Coordinator is responsible for executing research-based faculty onboarding, integration, and off-boarding activities. Provides an assortment of concierge services to new faculty members including move coordination, equipment management, lab planning, recruiting staff, assisting with IRB/IACUC/IBC protocol development and submission, and ensures faculty member is familiar with available resources at NCH. This position implements strategies to accelerate time to productivity and improves the faculty experience by ensuring smooth and seamless transitions. The Research Faculty Transition and Integration Coordinator will identify and recommends new program initiatives and interventions to enhance the effectiveness of activities.

Scientific Writer Sr.

Requisition ID: 2024-50110
Overview: Sr. Scientific Writer- CONNECT | CONNECT is an international collaborative network of pediatric cancer centers with the objective to improve outcomes for children with newly diagnosed and recurrent/progressive high-risk brain tumors The Operations center for this network is located at Nationwide Children’s Hospital in Columbus, OH. | | | CONNECT conducts small, scientifically rational, pilot studies to assess feasibility and early efficacy of incorporating promising new therapies into established frontline therapeutic regimens. CONNECT works alongside phase I consortia and large clinical trial groups to target high-risk pediatric and young adult tumors.

Veterinary Technician - Animal Resource Core

Requisition ID: 2024-50074
Overview: Veterinary Technician - Animal Resource Core | | General Description: Assist veterinarian, veterinary team lead and senior veterinary technician in providing veterinary care for a variety of laboratory animal species and technical support for research protocols.

Associate Director - Research- ARC

Requisition ID: 2024-50059
Overview: This position is multifaceted involving administrative, regulatory, and veterinary activities. This position develops and manages the clinical and technical veterinary program, including the aquatics program. In addition, provides clinical oversight/support for research animal care and use, medicine, disease, diagnosis, and experimental techniques for researchers at the Abigail Wexner Research Institute. Ensures research and clinical activities adhere to the United States Department of Agriculture (USDA), Public Health Service (PHS), and AAALAC rules and regulations. In the event the Director/Attending Veterinarian is absent, the Associate Director will assume all responsibilities to lead the department.

Research Associate - Center for Gene Therapy- Wein

Requisition ID: 2024-50052
Overview: The Wein Lab is focusing on Neuromuscular Disorders such as Duchenne Muscular dystrophy, which is a devastating disease leading to death of patients at age 20-30 years. Our lab developed an expertise in translational research, an emerging field which can be summarized as understanding the cause of a disease and learning from it in order to develop innovative therapeutic strategies. We are fully committed to continuing to integrate basic science and gene therapy skills in order to advance understanding and treatment of the muscular dystrophies. Our lab’s long term projects focus on RNA and DNA editing and gene transfer as therapies for neuromuscular disorders, as well as furthering fundamental research on muscle function. In particular, our lab uses the most recent technologies such as virus-mediated exon-skipping and the CRISPR/Cas9 genome editing tool. | We are looking for a highly motivated research associate who is energetic and intelligent to join our dynamic team. In particular, we are looking for someone with expertise in molecular biology (qPCR, IF, WB), as well as handling mouse colonies, mouse injection and dissection experiences to collect all muscles and peripheral organs. Experience in mounting muscle tissue is preferred. No background in gene therapy is required, however the candidate should have a high interest in human genetics and diseases and should be eager to learn and work on the bench in an independent manner. Finally, our team relies on good teamwork and therefore, the candidate should be a good communicator and team player. The job description includes, but is not restricted to performing research experiments, maintaining records of experiments, preparing laboratory reports, analyzing data and preparing publications and grants applications.

IGM Medical Laboratory Assistant- IGM

Requisition ID: 2024-49985
Overview: IGM Medical Lab Assistant | | We are seeking an IGM Medical Laboratory Assistant to join our team. The Medical Lab Assistant is responsible for clerical and patient care support tasks which enable technologists to complete testing of patient specimens in a timely manner.

Research Intern- RI Vaccines & Immunity Peeples

Requisition ID: 2024-49969
Overview: Provides assistance in research experiments under direction of Research Assistant; obtains supplies and equipment needed for research projects; maintains laboratory records.

Research Associate Sr.- Center for Gene Therapy - Harper

Requisition ID: 2024-49957
Overview: Senior Research Associate in Gene Therapy | | Employer: Center for Gene Therapy, The Abigail Wexner Research Institute at Nationwide Children’s Hospital | | Location: Columbus, Ohio, USA | | Salary: Competitive salary based on the candidate’s experience, benefits include family health insurance, matched retirement account | | Discipline: Life Sciences, Gene Therapy, Cellular and Molecular Biology, RNAi, CRISPR, Neurological diseases, Peripheral Neuropathy, neuromuscular diseases, Adeno-Associated Viral (AAV) vectors, Immunology, | | Start Date: As soon as possible | | Position Type: Full-time | | Organization Type: Non-profit | | The Harper Lab at the Center for Gene Therapy at Nationwide Children’s Hospital (NCH) is focused on developing gene therapies for muscular dystrophies and neuropathies. We are seeking a highly motivated, experienced, and independent Senior Research Associate to join our energetic, diverse and innovative team. We do molecular, cellular, and in vivo work. The ideal candidate will have experience in molecular biology and biochemistry (e.g. molecular cloning, western bloting, qPCR, various in vitro assays, and cell culture), as well as show talent or promise in scientific writing. Pre-clinical work in animal models may also be needed. This person will develop and validate new protocols for in vitro and in vivo experiments and will be responsible for training and directing junior lab members. A strong candidate will also have outstanding organization skills. | | The Harper Lab operates as a team and we promote and esprits de corps and work-life balance. Our philosophy centers on the notion that productivity is more important than time spent in the lab, and although we seek an individual capable of working on-site daily, we are open to flexible working hours. | | This position includes excellent retirement and health insurance benefits.

Post Doctoral Scientist Yr 1-3 - IGM Bedrosian

Requisition ID: 2024-49950
Overview: The Bedrosian lab in the Institute for Genomic Medicine is seeking a post-doctoral scientist to join our team. Our translational research group focuses on studying the genetics of epilepsy and other neurodevelopmental diseases using patient-derived tissue as well as murine models. We use cutting-edge techniques including single cell RNA-sequencing, spatial transcriptomics/proteomics, and other genomic techniques. The successful candidate will be engaged in projects exploring the molecular etiology of epilepsies through bioinformatic analysis of single-cell sequencing data and other genomic data. Prior experience with R and Seurat is preferred. The Institute for Genomic Medicine provides a stellar training environment with exposure to world-class expertise in genomics. We are a collaborative group with opportunities to build new skillsets and interact across the institute. Post-doctoral scientist will report to PI.

Research Purchasing Coordinator

Requisition ID: 2024-49935
Overview: The Purchasing Coordinator works under the supervision of the Purchasing Manager and is responsible for maintaining the efficient flow of purchase order requisitions and assisting with the placing of routine orders. This position works closely with internal customers to resolve order issues and supply interruptions. This position additionally works with Supply Chain staff to address supply concerns and update the SCIS system.

Post Doctoral Scientist - Gene Therapy/Neuroscience

Requisition ID: 2024-49922
Overview: EMPLOYER: Gene Therapy LaboratoryAbigail Wexner Research Institute, Nationwide Children’s Hospital (NCH). | | LOCATION: Columbus, Ohio, USA | | POSITION TYPE: Full-time | | PREFERRED START DATE: April 2024 | | DISCIPLINE: Gene Therapy | | ORGANIZATION TYPE: Non-profit | | RESEARCH DESCRIPTION: Our group is focused on developing novel gene therapy treatments for neuromuscular disorders and lysosomal storage disorders. We have recently developed and tested a novel gene therapy in patients with Duchenne Muscular Dystrophy and are currently developing treatments for Limb Girdle Muscular Dystrophy Type R9, GNE myopathy, and Lysosomal Acid Lipase Deficiency. This research involves basic and proof of concept studies in animal models for these diseases, as well as safety studies, with the goal of developing IND approvals for the testing of therapies in clinical trials. We collaborate with a team of other laboratories in Center for Gene Therapy and at Ohio State University to accomplish these goals. | | The successful candidate will have an excellent foundation in molecular and cellular biology and also in molecular and cellular pathology. We are particularly interested in candidates who also have experience analyzing animal models of disease and who understand the concepts relevant to design of disease therapies for muscle, liver, and/or brain disorders. As our lab focuses on diseases and therapies involving glycosylation, experience in glycobiology would be a major plus. Expertise in skeletal muscle or cardiac physiology, or AAV biology, would also be a major plus. To apply, please submit curriculum vitae, a cover letter indicating areas of expertise and a detailed statement of research interests and scientific accomplishments, and a list of 3 references. | | The selected candidate will be professional, self-motivated, and dedicated, with strong communication and interpersonal skills that will fit with our highly collaborative team. You will have many opportunities to learn new skill sets, present your work, develop professionally, and contribute to identifying new therapies for children with genetic disorders. | | **This position offers candidates to be involved in basic research and translation to the clinic** | | QUALIFICATIONS: | - Applicants must have an MD, Ph.D., or MD/PhD in a field of Biomedical or Life Sciences. | - Previous experience in a wet lab including work with cell cultures and animal models is required. | | COMPETENCIES, KNOWLEDGE, SKILLS, AND ABILITIES: | - Candidates should be capable of designing and carrying out high-level, complex research experiments independently. | - Expertise in lab techniques including, but not limited to, immunofluorescence, western blotting, ELISA, qPCR, qRT-PCR, flow cytometry, protein biochemistry, glycobiology, etc. | - Applicants with a good track record of publication are desirable, along with effective communication skills and scientific writing skills. | - Ability to train and mentor laboratory staff and graduate students. | - Writing and publishing scientific material, including manuscripts. | - Presenting research at regional, national, and international conferences. | - Contributing to grant submissions for external funding. | | We can offer potential candidates: | - Up to 5 years of salary support, to be renewed annually based on productivity | - Strong mentorship to support career development toward academia or industry jobs | - State-of-the-art laboratories and core facilities | - Possible affiliation with The Ohio State University College of Medicine | - Collaborative initiatives with clinical faculty

Lab Support Associate - RI Biopath Moyer

Requisition ID: 2024-49914
Overview: The Biopathology Center (BPC) within The Research Institute at Nationwide Children’s Hospital is a primarily grant-funded biorepository with the objective of acquisition and long-term storage of a large number of cancerous, normal and diseased biospecimens and related data. These biospecimens are used to support and facilitate cutting edge research and advancing clinical patient care. In accordance with provisions of approved protocols, the BPC currently serves as biorepositories for the Children’s Oncology Group (COG), NRG Oncology, SWOG (formerly the Southwestern Oncology Group), the Pediatric Division of the Collaborative Human Tissue Network (pCHTN), internal investigators, and other sponsor groups. This is a fast-paced, team-oriented laboratory that requires the ability to work well under pressure and maintain constant attention to detail. The position requires frequent communication via phone and email with submitting institutions as well as internal coordinating laboratories. This role does not perform hypothesis-based research or analysis on the biospecimens – we serve a supporting role to facilitate research. The Lab Support Associate is responsible for providing clerical and general support to the Biospecimen Processing and Receiving Laboratory. Duties include, but are not limited to, transportation of specimens, providing effective communication with regards to specimens and collection information, and providing an appropriate link to other lab sections when needed. Should project a professional image through direct and indirect communication to both internal and external Nationwide Children’s Hospital customers.

Research Associate - Research Childhood Cancer- Cassady

Requisition ID: 2024-49882
Overview: Research Assoc., Research Institute at Nationwide Children’s Hospital, Columbus, OH. Coordinate activities of tech & prof employees engaged in lab research. Ensure research experiments & lab analyses are performed in accordance w/guidelines. Conduct independent research studies & lab analysis. Set up research experiments. Collect & analyze data in accordance w/statistical procedures & prepare reports of results of studies. Collaborate & interact w/researchers onsite & at other research institutions. Prepare position papers about research studies, incl info about difficulties encountered in setting up & conducting research studies. Assist in prep of scientific publications & grant proposals w/regard to a specific area of research. Attend scientific conferences & give scientific presentations. Prepare budget proposals for supplies & equipment. Min. req incl: Bachelor’s in Biology, Molecular Biology, Microbiology or related, plus 2 yrs exp, incl ability to independently design & conduct experiments (in-vitro cell culture & molecular biology work, in-vivo animal work, such as implant tumors, inject tumors, resect tumors, perform intraperitoneal injections, collect & process animal organs, etc.); ability to collect & analyze data; ability to conduct immunological experiments (ELISA, flow cytometry); & knowledgeable in basic virology & in creating attenuated virus. Send resume to marsha.lutz@nationwidechildrens.org.

Research Assistant - Research Childhood Cancer- Drissi

Requisition ID: 2024-49861
Overview: Performs research experiments, plan and independently execute specialized laboratory research. To make accurate observations, to record test results, to analyze data, and to develop new methods. To guide the efforts of other laboratory personnel by explaining laboratory techniques and assisting in their experiments in accordance with provisions of the approved protocol; maintains records of experiments and prepares laboratory reports; assists in analyzing data and preparing publications.

Business Office Coordinator - Inst Mental & Beh Hlth

Requisition ID: 2024-49835
Overview: The Business Office Coordinator-Institute of Mental and Behavioral Health Research (IMBHR) is responsible for performing a wide variety of complex administrative tasks for assigned members of Senior Leadership within the IMBHR group. The BOC manages the daily operations of the corresponding departments and serves as the immediate supervisor of the administrative staff.

IGM Clinical Genomics Variant Analyst - NGS

Requisition ID: 2024-49807
Overview: The Clinical Genomics Variant Analyst is responsible for accurately identifying and classifying variants detected through the Institute for Genomic Medicine Clinical Laboratory genetic testing platforms. The Variant Analyst will review and document variants following practice guidelines under the direction of the laboratory Directors and Variant Scientists. . The Variant Analyst will assist with new test development and adapt responsibilities as related to changes in the field of genomics.

Financial Analyst/Data Analyst - RI Budgeting & Finance

Requisition ID: 2024-49798
Overview: The Financial Analyst works across all levels of the organization within Research and Hospital. The financial analyst will be directly involved with financial tracking and analysis of financial and data metrics across the entire research enterprise. The Financial Analyst is responsible for collecting, analyzing, and summarizing the financial implications of research operations. The Financial Analyst will be directly involved in the development and monitoring of annual capital and operating budgets including grant projections. The Financial Analyst will also be involved in the maintenance of the financial decision support system (TBD). Additionally, the financial analyst will assist in areas of finding cost efficiencies/streamlining staff efforts. The financial analysist will ensure that operations within the practice are consistent with Nationwide Children’s Hospital policies and practices in support of our mission and strategic plan.

Research Associate - Research Gene Therapy -Saad

Requisition ID: 2024-49778
Overview: Research Associate | | Summary | Dr. Nizar Saad at the Center for Gene Therapy at the Research Institute at Nationwide Children’s Hospital is seeking a talented research associate to join his lab. The Saad lab is engaged in research activities ranging from the development of viral and non-viral based gene therapy approaches for the treatment of neuromuscular diseases and other genetic diseases to the discovery of circulating molecular biomarkers for neuromuscular diseases. For further information on the Saad lab's research, please visit the lab website at https://www.nationwidechildrens.org/research/areas-of-research/center-for-gene-therapy/saad-lab. | The research associate should be able to conduct research and help in preparing research articles for publication; Ensures research experiments and laboratory analyses are performed in accordance with specific guidelines. Coordinates activities of technical and professional employees engaged in laboratory research.

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