ODS Senior Bioinformatics Scientist

The Abigail Wexner Research Institute- Office of Data Science (ODS)- White Lab

Join the Pioneering team at the Office of Data Science (ODS) at Nationwide Children's hospital, where we are at the forefront of the pediatric healthcare research innovation. At ODS, we seemlessly integrate a spectrum of data realms ---- spanning clinical, genomic, biobehavioral, public health, cardiovascular, infectious disease, cancer and translational research. Leveraging big data, AI and cloud computing, we're driving transformative breakthroughs in biomedical science to reshape pediatric healthcare. Our mission is to utilize the power of AI and big data not just to push the boundaries of health research but also to forge new frontiers in diagnostics and treatments, advocate for disease prevention, and champion health equity for all children.

We are seeking an experienced Senior Bioinformatics Scientist to spear-head cutting edge genomic research into rare genetic disorders and congential heart disease. This role involves applying machine learning to genomic data, statistical genetics, and the development and deployment of novel bioinformatic tools.The ideal candidate will contribute to  analyzing large patient cohorts with genome sequencing data, pushing the boundaries of pediatric healthcare research.  

The moment you walk through our doors, you feel it. When you meet our patient families, you believe it. And when you talk with anyone who works here, you want to be part of it. Welcome to Nationwide Children’s Hospital, Where Passion Meets Purpose.

Here, Diversity, Equity and Inclusion are integrated into our core values and practices. We are passionate about building, sustaining and evolving an inclusive and equitable environment. We are seeking individuals who live these values and want to share their experiences and efforts in support of our collective mission.

We’re 14,000 strong. And it takes every one of us to improve the lives of the kids we care for, and the kids around the world we’ll never meet. Kids who live healthier, fuller lives because of the knowledge we share. We know it takes a Collaborative Culture to deliver on our promise to provide the very best, innovative care and to foster new discoveries, made possible by the most groundbreaking research. Anywhere.

Ask anyone with a Nationwide Children’s badge what they do for a living. They’ll tell you it’s More Than a Job. It’s a calling. It’s a chance to use and grow your talent to make an impact that truly matters. Because here, we exist simply to help children everywhere.

Nationwide Children’s Hospital. A Place to Be Proud.

Core Responsibilities:

• Research and Development: Lead the innovation of computational and statistical methods for generating, analyzing, and interpreting genomic data. Design and implement sophisticated bioinformatics algorithms and software tailored to advancing our understanding of genetic diseases.
• Collaboration and Leadership: Act as a pivotal liaison between our data sciences research laboratory and our translational research collaborations, providing expertise in bioinformatics to translate complex genomic data into actionable insights. Drive projects from conception to completion, ensuring alignment with the Office of Data Sciences and White Lab strategic goals.
• Data Analysis and Pipeline Development: Utilize advanced computational genomics skills to:
  • Apply and adapt existing bioinformatics tools for NGS analysis, ensuring accurate downstream analysis and visualization.
  • Craft and maintain robust data analysis pipelines for diverse NGS protocols.
  • Innovate and benchmark new algorithms, enhancing our analytical capabilities.
  • Oversee the deployment of bioinformatics solutions on cloud computing platforms, with a focus on efficiency and scalability. Knowledge of Docker, AWS, and Spark is a plus.
• Communication and Collaboration: Exhibit exceptional communication skills to foster collaboration with scientists, clinicians, and developers. Contribute to scientific discussions, publications, and grant writing. Mentor junior bioinformatics staff and students, fostering a culture of learning and growth. Engage in community outreach to share findings and methods.

Qualifications

• Educational Background: A Ph.D. in Bioinformatics, Computational Biology, Biostatistics, or a related field, complemented by at least two years of postdoctoral experience. Candidates with a Master’s degree and significant relevant experience (10+ years) will also be considered.
• Technical Proficiency: Demonstrated expertise in NGS data analysis, strong command over UNIX/LINUX environments, and proficiency in scripting languages like Python. Familiarity with core bioinformatics tools, databases, and the R programming language is essential.
• Analytical Skills: Strong mathematical aptitude, abstract reasoning abilities, and hands-on approach to converting complex theoretical ideas into executable code. Experience with statistical analysis methods and experimental design is required. Experience in statistical modeling, machine learning, and natural language processing is a plus.
• Project Management: Proven ability to manage multiple projects in a dynamic environment, with a keen eye for detail and problem-solving.
• Collaborative Spirit: Strong interpersonal skills with a track record of productive collaborations across diverse teams. The ability to adapt communication styles to various audiences and cultural backgrounds is critical.

Join Us:

As a pivotal member of our team, your expertise will be instrumental in harnassing the data sciences to drive pediatric healthcare innovation. At ODS, you'll be part of a mission that transcends a conventional job- it's an opportunity to significantly impact children's health outcomes nationally.