Nationwide Children's Hospital

Senior Research Associate - RI Clin & Tran Jackson

Posted Date 4 weeks ago(9/24/2020 5:01 PM)
Requisition ID


Senior Research Associate


Our laboratory investigates the role of the renal urothelium in urinary tract obstruction. Specifically, we investigate the renal urothelium stem/progenitor and the molecular mechanisms governing urothelial development and repair. We are seeking a highly motivated and detail-oriented Senior Research Associate to perform bench research studies, analyze data and report experimental findings to the Principal Investigator. Applicants with experience managing a mouse colony, performing experiments on laboratory mice, and in flow cytometry and tissue culture are preferred. Preferred applicants will have an advanced degree, including a Master’s degree or PhD. Under the supervision of the Principal Investigator, the Senior Research Associate will design experiments, prepare samples and perform laboratory experiments investing the urothelial stem/progenitor cell in the kidneys and bladder. There will be a specific emphasis on using cell sorting techniques and organoid forming assays to evaluate the progenitor capacity of urothelial subpopulations. The Senior Research Associate will perform routine experimental procedures on laboratory animals, harvest tissue and use a variety of skills including techniques in molecular biology, physiology, genetics, microscopy, and biochemistry. The Senior Research Associate will compile results, prepare reports/present findings; maintain supply inventory; maintain glassware & laboratory equipment; and perform routine clerical duties to ensure the laboratory is safe and appropriately supplied.


Schedule: Full time, Benefits Eligible



Abigail Wexner Research Institute

700 Children’s Drive
Columbus, OH 43205



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  1. Performs basic and translational research experiments independently or semi-independently in accordance with protocols approved by the principal investigator. Such experiments may involve the use of laboratory animals, human subjects, or tissue culture.
  2. Effectively manages a mouse colony under the direction of the principal investigator and establishes/manages breeding colonies of genetically modified mice.
  3. Assists/performs routine experimental procedures on laboratory animals, including the administration of drugs and experimental urinary tract obstruction.
  4. Collects mouse tissue, urine, and other samples as needed. Such activities may be performed independently.
  5. Has experience with basic laboratory techniques – including genotyping, real-time PCR, Western blot, and tissue culture. Experience with flow cytometry, 3D tissue cultures, RNAseq, bioinformatics, or laser capture microdissection would be an advantage.
  6. Ensures accuracy of laboratory analytical procedures as required by specific research projects. Maintains accurate daily logs of experiments including methods, results, and conclusions.
  7. Interprets the results of data analyses with input from the principal investigator.
  8. Drafts and/or assists the principal investigator in the preparation of scientific publications and grant proposals.
  9. Makes recommendations about refinement and/or replacement of laboratory analytical procedures. Implements such refinements or new procedures with input from the principal investigator.
  10. Gathers information for supplies needed to conduct research, maintains inventory of equipment and supplies, and assures that research equipment is in good working order.
  11. Collaborates in the preparation of research budgets, and monitors expenditure of funds to assure that studies are conducted within budgetary constraints.
  12. Instructs other laboratory workers and students in standard methods, practices, procedures, and equipment operations.
  13. Maintains a clean and safe working area and performs general laboratory maintenance. Adheres to proper safety techniques and procedures.
  14. Performs miscellaneous related duties.





  • Master’s Degree or PhD in a relevant field of science from an accredited college with a minimum of one year of relevant laboratory experience OR Bachelor of Science degree with two to three years of laboratory research experience.


Preferred Experience:

  • Coursework in anatomy, physiology, biochemistry, statistics, relevant research methods desirable.


Minimum Physical Requirement:


100% Kneeling / reaching

100% Finger dexterity

100% Talking / hearing / seeing

33% Lifting / carrying weight 0-20 pounds for 1-5 minutes


Percent of time spent on:

40% Performing research work

30% Designing and developing protocols

20% Recording data, and analyzing/interpreting results

5% Preparing scientific papers/abstracts/presentations

03% Miscellaneous paperwork and administrative duties (related to inventories and research safety) 02% Instructing other lab personnel


The above list of duties is intended to describe the general nature and level of work performed by individuals assigned to this classification. It is not to be construed as an exhaustive list of duties performed by the individual so classified, nor is it intended to limit or modify the right of any supervisor to assign, direct, and control the work of employees under his/her supervision.




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