Nationwide Children's Hospital

Post Doctoral Scientist - RI CC Theisen

Posted Date 1 month ago(9/21/2020 5:27 PM)
Requisition ID


Post Doctoral Scientist – Center for Childhood Cancer


The Theisen Lab is recruiting for postdoctoral positions in the Center for Childhood Cancer at Nationwide Children’s Hospital. Our group focuses on chromatin and epigenetic regulation, and interventions targeting that regulation, in pediatric cancer. Our training environment is highly collaborative and interdisciplinary, with opportunities to pursue both basic and translational projects at the intersection of cancer biology, genomics, epigenetics, and proteomics. The ideal candidate will be independent, motivated, and able to plan and carry out hypothesis-driven research projects.


This individual works under the mentorship of an established AWRI principal investigator to become familiar with the background literature and design experiments and develop protocols to conduct research related to epigenetics and chromatin regulation in pediatric cancer.  This candidate is expected to: develop hypotheses for further investigation from the results of studies, develop hypotheses for further investigation; prepare technical materials such as abstracts, annual reports, scientific papers and presentations; publish scientific articles in appropriate refereed journals; independently write and/or contribute to grant proposals; work toward independence in his/her research effort; and obtain external research funding.  Appointment as a Post Doc is a maximum of 5 years in length. Email for more information.


We are currently seeking individuals with interest in proteomics, the biology of chromatin regulatory complexes, 3D tissue culture, or organoid systems. Previous experience and demonstrated skills in any of these areas will be valued in candidates.


Schedule: Full time, Benefits Eligible



Abigail Wexner Research Institute

700 Children’s Drive
Columbus, OH 43205

Why Nationwide Children's Hospital?

Why Nationwide Children’s Hospital

The moment you walk through our doors, you can feel it. When you meet one of our patient families, you believe it. And when you talk with anyone who works here, you want to be part of it, too. Welcome to Nationwide Children’s Hospital, where Passion Meets Purpose.

Here, Everyone Matters. We’re 12,000 strong. And it takes every single one of us to improve the lives of the kids we care for, and the kids from around the world we’ll never even meet. Kids who are living healthier, fuller lives because of the knowledge we share. We know it takes a Collaborative Culture to deliver on our promise to provide the very best, innovative care and to foster new discoveries, made possible by the most groundbreaking research. Anywhere.

Ask anyone with a Nationwide Children’s badge what they do for a living. They’ll tell you it’s More Than a Job. It’s a calling. It’s a chance to use and grow your talent to make an impact that truly matters. Because here, we exist simply to help children everywhere.

Nationwide Children’s Hospital. A Place to Be Proud



With guidance from a AWRI mentor, design experiments and develops protocols required to conduct productive research in pediatric cancer biology.  After the study has been designed, performs the research work in accordance with the protocol.



Helps to train and supervise technical support staff in performing specific techniques essential to carrying out the research program.



Records and analyzes data generated by the research study and helps to plan future research endeavors.



Prepares scientific and technical papers from the results of the research work.  Publishes papers in appropriate refereed scientific journals. Presents findings at local (particularly AWRI research meetings) and national research forums.



If appropriate, collaborates with other ongoing research efforts either at AWRI or at The Ohio State University.



This is considered a training position therefore the AWRI will allow a trainee 5 years to advance beyond the level of Post Doc.



Works toward research independence. Prepares to submit proposals to and obtain funding from external granting agencies.





  1. MD, Ph.D, Pharm.D., or equivalent degree.

Required Experience:

  1. Ability to do technical writing, and good communication skills. Must be computer literate.
  2. Ability to collaborate with other scientists at NCH/OSU.
  3. Ability to work with Dr. Theisen to develop project goals.
  4. Contribute to regular group meetings and journal clubs.
  5. General experience with nucleic acids (DNA/RNA) and proteins, tissue culture, molecular biology techniques (cloning, PCR, immunoblotting, etc.), biochemistry, protein purification, and ability to follow and troubleshoot established protocols.
  6. Experience or interest in learning genomics techniques and the basic bioinformatic requirements to process data including ChIP-seq, CUT&RUN, CUT&Tag, ATAC-seq, Hi-C, RNA-seq.
  7. Experience or interest in learning new proteomics techniques.
  8. Experience or interest in translational research, with a focus on animal models of human cancer.


Minimum Physical Requirement:


Percent of time spent on:

20%     Designing and developing protocols

30%     Performing research work

30%     Recording and analyzing data generated by research study

15%     Preparing scientific and technical papers

03%     Liaison with OSU researchers

02%     Miscellaneous paperwork associated with research


Minimum physical requirements:

100%    Kneeling / reaching

100%    Finger dexterity

100%    Talking / hearing / seeing

33%     Lifting / carrying weight 0-20 pounds for 1-5 minutes


Pressure in this position will vary depending on the workload.  The workload will be heavy but manageable most of the time.  Pressure may arise in the face of deadlines associated research and manuscript writing. 


The above list of duties is intended to describe the general nature and level of work performed by individuals assigned to this classification.  It is not to be construed as an exhaustive list of duties performed by the individual so classified, nor is it intended to limit or modify the right of any supervisor to assign, direct, and control the work of employees under his/her supervision.






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