Nationwide Children's Hospital

  • Post Doctoral Scientist - Gene Therapy/Neuromuscular Research

    Posted Date 6 days ago(12/5/2018 11:33 AM)
    Requisition ID
  • Overview

    The Flanigan Laboratory at the Center for Gene Therapy at Nationwide Children’s Hospital (NCH) is seeking highly motivated post-doctoral fellows to be involved with cutting edge studies in muscular dystrophies and other neuromuscular disorders.


    These studies emphasize both basic and translational research, and the ideal candidate will have experience in molecular, cellular, or AAV biology, with expertise in tissue culture and animal models of muscle and neurologic diseases. Current projects include ones directed toward therapeutic initiation of altered translation of the dystrophin protein; AAV-based gene replacement for certain limb-girdle muscular dystrophies and other muscle diseases; and clinical AAV-based gene transfer studies.


    This position is within a moderate-sized laboratory that is highly energetic, testing innovative strategies to understand and treat muscular dystrophies. The lab is part of an NIH (NIAMS) P50-funded Center of Research Translation in Muscular Dystrophy Therapeutic Development (, housed in the Research Institute at NCH.


    The training environment is excellent, with extensive collaboration among researchers within the Center for Gene Therpapy as well as close collaboration among scientists at both NCH and Ohio State University, facilitated by (


    The moment you walk through our doors, you can feel it. When you meet one of our patient families, you believe it. And when you talk with anyone who works here, you want to be part of it, too. Welcome to Nationwide Children’s Hospital, where Passion Meets Purpose.

    Here, Everyone Matters. We’re 12,000 strong. And it takes every single one of us to improve the lives of the kids we care for, and the kids from around the world we’ll never even meet. Kids who are living healthier, fuller lives because of the knowledge we share. We know it takes a Collaborative Culture to deliver on our promise to provide the very best, innovative care and to foster new discoveries, made possible by the most groundbreaking research. Anywhere.

    Ask anyone with a Nationwide Children’s badge what they do for a living. They’ll tell you it’s More Than a Job. It’s a calling. It’s a chance to use and grow your talent to make an impact that truly matters. Because here, we exist simply to help children everywhere.

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    • With guidance from a CRI mentor, design experiments and develops protocols required to conduct productive research in a specific scientific area.  After the study has been designed, performs the research work in accordance with the protocol.  
    • Helps to train and supervise technical support staff in performing specific techniques essential to carrying out the research program.  
    • Records and analyzes data generated by the research study, and helps to plan future research endeavors.  
    • Prepares scientific and technical papers from the results of the research work. 
    • Publishes papers in appropriate refereed scientific journals.  
    • Presents findings at local (particularly CRI research meetings) and national research forums.  
    • If appropriate, collaborates with other ongoing research efforts either at CRI or at The Ohio State University.  
    • This is considered a training position therefore the RI will allow a trainee 5 years to advance beyond the level of Post Doc.  
    • Works toward research independence. Prepares to submit proposals to and obtain funding from external granting agencies. 

    Reports to: Either established CRI principal investigator (i.e. OSU faculty member) or a CRI Senior Research Scientist for guidance in research endeavors   To apply, please send your curriculum vitae and a list of three references (including contact information) to Dr. Kevin Flanigan (


    1. PhD in Biomedical Engineering, Biomedical Sciences or related Science field. 

    2. Necessary technical skills in the appropriate area of research.

    3. Ability to do technical writing, and good communication skills.  


    Minimum Physical Qualifications: Percent of time spent on: 25%     Designing and developing protocols 25%     Performing research work 25%     Recording and analyzing data generated by research study 10%     Preparing scientific and technical papers 03%     Liaison with OSU researchers 02%     Miscellaneous paperwork associated with research   Minimum physical requirements: 100%   Kneeling / reaching 100%   Finger dexterity 100%   Talking / hearing / seeing   33%   Lifting / carrying weight 0-20 pounds for 1-5 minutes   Pressure in this position will vary depending on the workload.  The workload will be heavy but manageable most of the time.  Pressure may arise in the face of deadlines associated research and manuscript writing.                                                                 


    The above list of duties is intended to describe the general nature and level of work performed by individuals assigned to this classification.  It is not to be construed as an exhaustive list of duties performed by the individual so classified, nor is it intended to limit or modify the right of any supervisor to assign, direct, and control the work of employees under his/her supervision. 


    EOE M/F/Disability/Vet


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