The Institute for Genomic Medicine at Nationwide Children’s Hospital is paving the way for a future that integrates genomics into the everyday practice of pediatrics in which genetic sequencing is a standard of care. The IGM is housed in the campus’ newest research building, spanning ~25,000 square feet of laboratory and office/desk space in a highly interactive setting. The Technology Development Group supports the Institute’s laboratory and sequencing needs, designing cutting edge genomic applications and research in the area of human health.
The team is looking for a full time technology development specialist with automation expertise in assay design, instrument scripting, production processes and validation controls. The preferred candidate will be able to adjust assay parameters improving instrument precision and accuracy. Automation processes will include a variety of next-generation preparatory methods as part of the IGM commitment to excellence in pediatric care. Therefore, the candidate must possess strong aptitudes in molecular biology and next generation sequencing approaches.
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Demonstrates the technical and computer skills required in the laboratory:
• Develops, verifies, writes reviews and/or updates procedures as necessary.
• Assists and/or oversees in the development and/or implementation of new tests, procedures or instrumentation within the Institute for Genomic Medicine.
• DNA/RNA sample quality control.
• Next-generation sequencing (NGS) library preparation: Automated processing of whole genome (WGS), RNA-Seq, and Enrichment (exome/panels) libraries.
• Use of Laboratory Information Management Software (LIMS) to record project details, monitor laboratory equipment performance, and assist with ordering supplies/reagents.
• The position requires interaction with collaborators and company representatives.
• Work under the mentorship of the Principal Investigator and Technical Director to perform experiments and conduct research.
• Demonstrates knowledge of and upholds applicable laws and regulations related to position. Maintains knowledge of techniques, procedures, and protocols, lab-wide and within lab section. Reviews and acknowledges procedures as required. Assists with procedure and technical development and acts as a resource.
• Performs routine and complex technical procedures and functions in the laboratory information system in an adequate and timely manner. Performs preventive maintenance and quality control with appropriate documentation and communication.
• Demonstrates proficiency in operating, cleaning, maintenance and scripting of instrumentation.
• Designs and modifies script to ensure accurate and precise automation controls and quality of analysis.
• Demonstrates increased productivity relative to experience.
• Assists in the selection of additional or replacement equipment and specialized supplies.
• Implements new procedures to adapt to the developments in clinical research applications.
• Continuously improves the quality of the services offered.
Demonstrates knowledge of and upholds applicable laws and regulations related to the position
• Troubleshoots (e.g. instrumentation) and assists in problem resolution. Arranges as necessary for service by biomedical engineering or appropriate external vendors
• Follows the established guidelines within the department for safety, PPE, SOP (standard operating procedures), material labeling and problem / solution documentation.
Demonstrates the ability to communicate with staff, patients, parents, and clients.
• Displays a positive attitude and supports the goals and policies of the department / institution
• Demonstrates the ability to present information, whether oral or written, in a clear, concise and effective manner to coworkers and management.
• Demonstrates, maintains and fosters interpersonal relationships with internal and external customers.
• Demonstrates ability to change manner of communication style to adapt to various cultural differences as needed
• Demonstrates respect for coworkers
• Provides courteous and informative customer service
• Prioritizes and adjusts schedule in order to accommodate projects.
• Demonstrates the ability to adjust to change, handle interruptions and function with changing circumstances.
• Demonstrates the initiative and ability to provide feedback that is useful and assists in individual improvement.
• Assist with training of new employees, students, fellows, rotators, etc.
• Promotes a cohesive work environment and identify resolutions to improve moral.
Demonstrates the ability to plan and show initiative.
• Takes the initiative and demonstrates the ability within the department to solve problems effectively and in a timely manner.
• Promote a cohesive work environment and identify resolutions to improve morale in cooperation with supervisors / manager
• Maintains appropriate inventory levels for optimal laboratory usage.
• Responsible for presenting continuing education. Participates in special projects and presentation of results. Assists with development and monitoring of specific competencies. Required to complete at least four hours of medical/technical continuing education, yearly.
• Demonstrates the ability to make determinations regarding course of action and alternatives by addressing problems by using resolutions and basic troubleshooting skills. Able to resolve technical, computer, and service problems with in the lab section. Performs in-depth problem solving.
• Attends local, regional, and national meetings of relevance to the Institute for Genomic Medicine.
Prefer Master’s degree in science in an appropriate filed or in medical technology with two years relevant experience in a similar clinical laboratory OR Bachelor’s degree with a science major or in medical technology with at least five years of relevant experience in a similar laboratory.
Must have a strong interest in Research Biology, Computational Biology or Medicine and some experience with computer science as well as a good understanding of molecular biology, genetics, genomics or computational biology.
Additional Qualifications Required
• Experience with molecular biology laboratory skills.
• Experience with automated liquid handling instrumentation
• Exceptional attention to detail and high-level organizational skills.
• Strong communication skills (both oral and written), a service based orientation.
• Positive attitude/team player.
• Ability to multi-task.
• Proficient in computer skills
• Desire to learn and contribute to cutting edge pediatric research.
Hours: Full-time, hours negotiable
MINIMUM PHYSICAL REQUIREMENTS
Note frequency as Constantly (67-100%), Frequently (34-66%) and Occasionally (0-33%) for each requirement. Also note any lifting requirements with pound limit.
Percent of time spent on: 50% Typing on computer 50% Lab work
Minimum physical requirements: 100% Kneeling / reaching 100% Finger dexterity 100% Talking / hearing / seeing 33% Lifting / carrying weight 0-20 pounds for 1-5 minutes 33% Pushing a cart with weight 50-100 pounds for 5-10 minutes
The above list of duties is intended to describe the general nature and level of work performed by individuals assigned to this classification. It is not to be construed as an exhaustive list of duties performed by the individual so classified, nor is it intended to limit or modify the right of any supervisor to assign, direct, and control the work of employees under his/her supervision.