Nationwide Children's Hospital

  • Senior Research Associate - RI Gene Ther Wein

    Posted Date 2 months ago(10/2/2018 10:07 AM)
    Requisition ID
  • Overview

    Full Time, Benefit Eligible


    Senior Research Associate:

    The Wein Lab is focusing on Neuromuscular Disorders such as Duchenne Muscular dystrophy, which is a devastating disease leading to death of patients at age 20-30 years. Our lab developed an expertise in translational research, an emerging field which can be summarized as understanding the cause of a disease and learning from it in order to develop innovative therapeutic strategies. We are fully committed to continuing to integrate basic science and gene therapy skills in order to advance understanding and treatment of the muscular dystrophies. Our lab long term project focus on RNA and DNA editing and gene transfer as therapies for neuromuscular disorders, but it will also include more fundamental research on muscle function. In particular, our lab uses most recent technologies such as virus-mediated exon-skipping and the CRISPR/Cas9 genome editing tool.

    We are looking for a highly motivated senior research associate who is energetic and intelligent to join our dynamic team. In particular, we are looking for someone with molecular biology, cell culture in neuromuscular disorders field as well as animal housing, handling, injection and dissection experiences. Experience in dissecting and mounting muscle tissue is also preferred. No background in gene therapy is required, however the person should have a high interested in human genetics and diseases and should be eager to learn and work on the bench in an independent manner. Also the person should be a good communicator, team player and be able to work independently. The job description includes, but is not restricted to performing research experiments, maintaining records of experiments, preparing laboratory reports; assisting in analyzing data and preparing publications.


    Why Nationwide Children's? The moment you walk through our doors, you can feel it. When you meet one of our patient families, you believe it. And when you talk with anyone who works here, you want to be part of it, too. Welcome to Nationwide Children’s Hospital, where Passion Meets Purpose.

    Here, Everyone Matters. We’re 12,000 strong. And it takes every single one of us to improve the lives of the kids we care for, and the kids from around the world we’ll never even meet. Kids who are living healthier, fuller lives because of the knowledge we share. We know it takes a Collaborative Culture to deliver on our promise to provide the very best, innovative care and to foster new discoveries, made possible by the most groundbreaking research. Anywhere.

    Ask anyone with a Nationwide Children’s badge what they do for a living. They’ll tell you it’s More Than a Job. It’s a calling. It’s a chance to use and grow your talent to make an impact that truly matters. Because here, we exist simply to help children everywhere.

    Nationwide Children’s Hospital. A Place to Be Proud

    Job Duties:

    Conducts independent research studies and laboratory analysis in a specific area agreed upon in conjunction with a principal investigator. Sets up research experiments and arranges subjects to be used in research experiments through appropriate hospital and research institute procedures. Collects and analyzes data in accordance with appropriate statistical procedures, and prepares reports, inclusive of graphs, tables, and photographs, of the results of studies. Collaborates and interacts with other researchers doing similar studies at CRI and at other research institutions. Prepares position papers about research studies including information about difficulties encountered in setting up and conducting research studies. Assists in the preparation of scientific publications and grant proposals with regard to a specific area of research. Attends scientific conferences and gives scientific presentations. Serves as a resource person for other investigators and as a mentor to less experienced research personnel. Prepares budget proposals for supplies and equipment needed to conduct research. Monitors study expenditures to assure that budgetary constraints are followed. Performs miscellaneous related duties as required.




    Master of Science degree with one to two years of laboratory research experience OR Bachelor of Science degree with two to three years of laboratory research experience OR certification and experience may be considered in lieu of formal education. Must be able to use research methods in generating and collecting data and analyzing the data for report preparation. Must be able to develop complex position papers and reports, and help in preparation of research grant proposals and scientific publications.



    Percent of time spent on: 50% Conducting research studies 25% Collecting and analyzing data 10% Preparing position papers, publications and grant proposals 05% Resource person for other investigators 05% Mentoring less experienced research personnel 05% Purchasing supplies Minimum physical requirements: 100% Kneeling / reaching 100% Finger dexterity 100% Talking / hearing / seeing 33% Lifting / carrying weight 0-20 pounds for 1-5 minutes.


    The above list of duties is intended to describe the general nature and level of work performed by individuals assigned to this classification. It is not to be construed as an exhaustive list of duties performed by the individual so classified, nor is it intended to limit or modify the right of any supervisor to assign, direct, and control the work of employees under his/her supervision. EOE M/F/Disability/Vet


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