Nationwide Children's Hospital

  • Research Assistant - Clinical & Translational Research

    Posted Date 2 months ago(9/27/2018 2:47 PM)
    Requisition ID
  • Overview

    Full Time, Benefit Eligible


    Research Assistant: We are seeking a highly motivated individual to join our research lab in the study of coagulation derangements and coagulation enzyme signaling in glomerular disorders, which are a leading cause of kidney disease and death. The successful applicant must possess an exceptional work ethic and desire to learn new research techniques. Ability to work independently and in collaboration with a team of researchers is a must. Duties include, but are not limited to, performing complex experimental techniques and procedures including molecular biology, cell biology, and biochemistry. Experience working with rodent (mouse and rat) disease models a plus. Expertise with cell culture, genetic engineering, and gene expression profiling preferred. The laboratory’s approaches include integration of cell biology, molecular biology, and animal disease models. Post-educational, real world experience with molecular biology, cloning, mutagenesis, and protein expression/purification is a must, persons without experience in these areas will not be considered. The successful candidate will confer regularly with the principal investigator and other members of the research team, but must incorporate self-directed research, excellent technical, presentation, and communication skills as essential parts of the job. 


      A Bachelor’s degree in a relevant field of science from an accredited college or university is preferred. Must have six months to two years of previous laboratory experience in molecular and cellular biology including PCR, RT-PCR, Western-blotting, flow cytometry, cell culture, and genetic engineering. Experience with recombinant DNA engineering and transfection of mammalian cell lines a plus. Coursework in biochemistry, anatomy, physiology, statistics, and relevant research methods are desirable. The qualified individual will perform research experiments to study disease mechanisms and evaluate potential therapeutics in accordance with the needs of overall projects; maintain records of experiments and prepare/present laboratory reports; assist in analyzing data and preparing publications.


    Why Nationwide Children's? The moment you walk through our doors, you can feel it. When you meet one of our patient families, you believe it. And when you talk with anyone who works here, you want to be part of it, too. Welcome to Nationwide Children’s Hospital, where Passion Meets Purpose.

    Here, Everyone Matters. We’re 12,000 strong. And it takes every single one of us to improve the lives of the kids we care for, and the kids from around the world we’ll never even meet. Kids who are living healthier, fuller lives because of the knowledge we share. We know it takes a Collaborative Culture to deliver on our promise to provide the very best, innovative care and to foster new discoveries, made possible by the most groundbreaking research. Anywhere.

    Ask anyone with a Nationwide Children’s badge what they do for a living. They’ll tell you it’s More Than a Job. It’s a calling. It’s a chance to use and grow your talent to make an impact that truly matters. Because here, we exist simply to help children everywhere.

    Nationwide Children’s Hospital. A Place to Be Proud

    Job Duties:


    Performs research experiments independently or semi-independently in accordance with protocols approved by the principal investigator. Such experiments may involve the use of laboratory animals or human subjects any may require evening and/or weekend duties. Prepares and tests substrate, conducts assays, and prepares tissue cultures for use in research studies. Collects blood, urine, and other samples as needed. Such activities may be performed independently and may require evening and weekend hours. Ensures accuracy of laboratory analytical procedures as required by specific research projects. Collects and controls experimental data and patient information; and maintains accurate daily logs of experiments including methods, results, and conclusions. Interprets the results of data analyses with input from the principal investigator. Assists the principal investigator in the preparation of scientific publications and grant proposals. Make recommendations about refinement and/or replacement of laboratory analytical procedures. Implements such refinements or new procedures with input from the principal investigator. Orders supplies needed to conduct research; maintains inventory of equipment and supplies; and assures that research equipment is in good working order. Collaborates in the preparation of research budgets, and monitors expenditure of funds to assure that studies are conducted within budgetary constraints. Instructs other laboratory workers and students in standard methods, practices, procedures, and equipment operations. Maintains a clean working area and performs general laboratory maintenance. Adheres to proper safety techniques and procedures. Performs miscellaneous related duties.


    Reports to the Principal Investigator. Administratively reports to the CRI Vice President. CONTACTS: (Indicate the internal and external contacts, other than the immediate supervisor and subordinate staff, with whom this position interacts) Internal: All departments within Children’s Hospital, OSU and Outreach Centers. External: Vendors. There will be daily access to confidential information. Disclosure could lead to legal implications.


    MINIMUM QUALIFICATIONS: (Indicate the minimum levels and areas of education, experience, knowledge, skills, and abilities required at the time of hire for an individual to perform at an acceptable level of proficiency in this position. Be sure to list any registrations, certifications or licensures required. Additional qualifications may be included; however, they must be designated as “desirable”.)

    1. Associate’s degree in Veterinary Technology, Medical Laboratory Technology, Biotechnology or a relevant field of science from an accredited college.

    2. Six months to two years of relevant laboratory experience.

    3. Coursework in anatomy, physiology, statistics, relevant research methods and radiation desirable. AGE(s) OF PATIENTS SERVED: Yes X No Does this position have some responsibility for the assessment, treatment, or care of pediatric and selected adult patients.


    MINIMUM PHYSICAL REQUIREMENTS: (List the minimum physical requirements necessary to perform the essential functions of the position. Physical requirements may include lifting, carrying, pushing, kneeling, reaching, finder dexterity, talking, hearing, seeing, etc. If possible, minimum physical requirements should be described in terms of the amount (e.g., weight) and duration (e.g., occasionally = 0-33%, frequently = 34-66%, constantly = 67-100%) of specific physical effort required to perform the essential functions. For example: “lifts objects weighing up to 30 pounds. – Constantly”. Percent of time spent on: 50% Preparing test substrates, conducting assays, preparing cultures 25% Interpreting results of data analyses with PI 11% Miscellaneous paperwork associated with research 10% Ordering supplies 02% Preparation of budget 02% Instructing other lab personnel Minimum physical requirements: 100% Kneeling / reaching 100% Finger dexterity 100% Talking / hearing / seeing 33% Lifting / carrying weight 0-20 pounds for 1-5 minutes Pressure in this position will vary depending on the workload. The workload will be heavy but manageable most of the time. Pressure may arise in the face of deadlines.


    The above list of duties is intended to describe the general nature and level of work performed by people assigned to this classification. It is not to be construed as an exhaustive list of duties performed by the people so classified, nor is it intended to limit or modify the right of any supervisor to assign, direct and control the work of employees under his/her supervision. EOE M/F/Disability/Vet


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